Makhachev v Della Maddalena Betting Odds

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UFC 322 takes place November 16, 2025, in Las Vegas, with one of the most intriguing matchups of the year: Jack Della Maddalena defending his welterweight crown against lightweight king Islam Makhachev. The storyline writes itself - Makhachev moving up in weight to chase double-champ status, Della Maddalena standing tall as the division's sharpest striker.

Makhachev has cleaned out the lightweight division. His last defense, a dominant win over Arman Tsarukyan, reaffirmed his control at 155 pounds. Now, he's aiming for new territory. The Dagestani champion's wrestling, cage control, and relentless pace have broken opponents for years. But at 170, he'll be giving up size and natural strength against a polished technician with serious knockout power.

Jack Della Maddalena is fresh off a knockout win over Vicente Luque in Sydney, a performance that reminded everyone how dangerous his boxing really is. Crisp combinations, precise timing, and excellent footwork - he's made elite welterweights look outmatched. Still, this is no ordinary challenger. Makhachev's transition to welterweight adds a fascinating layer to a fight that already sells itself.

Source: Bet365
Time Stamp: 27 October 2025 8:46 am
Odds Subject to Change

According to Bet365, Jack Della Maddalena is listed at 3.25, while Islam Makhachev enters as the 1.36 favorite. That translates to implied odds of 73.5% for Makhachev and 30.8% for Della Maddalena. For a fighter moving up in weight, those numbers show just how much respect the market gives Makhachev's skill set and discipline.

The key question: how will the size difference play out? Della Maddalena will likely hold the advantage in reach, power, and durability at this weight. Makhachev will rely on timing and grappling to close the gap, looking to drag the Australian into deep water. The first round could set the tone - if Makhachev gets early control, it becomes his fight. If Della Maddalena keeps distance and forces extended exchanges, his chances rise sharply.

From a betting perspective, Makhachev by decision is the expected route for conservative bettors. Della Maddalena by KO/TKO, however, offers pure value. Few expect the champion to submit the Australian from his back, and if Makhachev's wrestling doesn't translate perfectly at 170, we could see fireworks.

This isn't just another title fight - it's a clash between dominance and ambition, precision and pressure. The odds say Makhachev's skill will carry up a division. But if the weight jump dulls his strength, Della Maddalena has all the tools to flip the script.


Fight Details:

Date: 16 November 2025
Event: UFC 322
Venue: Las Vegas